My publications & presentations

Journal articles

Messenger RNA-encoded antibody approach for targeting extracellular and intracellular tau

Brain Communications · 2024 · First author

In my first-author study, we used synthetic mRNA to express RNJ1 as a secreted antibody and an intracellular fragment, and demonstrated tau engagement in human cells.

Wongsodirdjo, P., Caruso, A. C., Yong, A. K., Lester, M. A., Vella, L. J., Hung, Y. H. & Nisbet, R. M. (2024). Brain Communications, 6(2), fcae100.

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Our published graphical abstract showing mRNA synthesis, transfection and expression of tau-specific antibodies. — Our graphical abstract: from synthetic mRNA to tau-binding antibodies.

Our graphical abstract: from synthetic mRNA to tau-binding antibodies.

Small extracellular vesicles contain metals and transfer metal intercellularly

Journal of Extracellular Biology · 2024 · Co-author

I co-authored this study of metals in small extracellular vesicles. We found that these vesicles contain essential and non-essential metals and can transfer metal between cells.

Purnianto, A., Mawal, C., Kulkarni, M. M., Su, H., Koukoulis, T. F., Wongsodirdjo, P., Hung, Y. H., Ayton, S., Bush, A. I., Barnham, K. J. & Vella, L. J. (2024). Journal of Extracellular Biology, 3(10), e70012.

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